ABSTRACT
ERK pathway regulated the programmed death ligand-1 (PD-L1) expression which was linked to the response of programmed death-1 (PD-1)/PD-L1 blockade therapy. So it is deducible that ERK inhibitor could enhance the efficacy of PD-1 inhibitor in cancer immunotherapy. In this study, PD0325901, an oral potent ERK inhibitor, strongly enhanced the efficacy of PD-1 antibody
ABSTRACT
In order to reduce the working intensity of medical staff in inspecting patients during traditional infusion, a remote monitoring system for intravenous infusion is designed for solving the problem of delay in handling treatment during infusion process and to reduce the incidence of medical accidents. The system uses Visual Basic.NET language to develop the upper computer platform for infusion monitoring. It uses the Arduino control board and infrared photoelectric sensor to form a monitoring device to detect relevant information. At the same time, it uses Zigbee wireless sensing technology to transmit data and upload it to the software platform. The results show that the system can receive data from multiple monitoring terminal devices in the upper computer platform application interface at the same time. It can display the data in the nurse station in a graphical way, and perform alarm warning and information storage during the infusion process. The infusion monitoring system can observe the monitoring situation in real time, reduce the workload of medical staff, and further improve the operating efficiency and safety of the hospital.